Gando S, Wada T: Pathomechanisms Underlying Hypoxemia in Two COVID-19-Associated Acute Respiratory Distress Syndrome Phenotypes: Insights From Thrombosis and Hemostasis. Shock 57:1- 6,2022
原著（英文）
Nakahashi S, Imai H, Shimojo N, Magata Y, Einama T, Hayakawa M, Wada T, Morimoto Y, Gando S: Effects of the Prone Position on Regional Neutrophilic Lung Inflammation According to 18F-FDG Pet in an Experimental Ventilator-Induced Lung Injury Model. Shock 57:298-308,2022
Mikami R, Imai S, Hayakawa M, Sugawara M, Takekuma Y: Clinical applicability of urinary creatinine clearance for determining the initial dose of vancomycin in critically ill patients. J Infect Chemother 28:199-205,2022
Takauji S, Tanaka H, Hayakawa M, Horioka K, Isozaki S, Konishi H: Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model. Biochem Biophys Res Commun 587: 1-8,2022
Fujita M, Maeda T, Miyata S, Mizugaki A, Hayakawa M, Miyagawa N, Ushio N, Shiraishi A, Ogura T, Irino S, Sekine K, Fujinami Y, Kiridume K, Hifumi T, Kushimoto S: Association of Trauma Severity with Antibody Seroconversion in Heparin-induced Thrombocytopenia: A Multicenter, Prospective Observational Study. J Trauma Acute Care Surg 93:402-408,2022
Tsuchida T, Wada T, Mizugaki A, Oda Y, Kayano K, Yamakawa K, Tanaka S: Protocol for a Sepsis Model Utilizing Fecal Suspension in Mice: Fecal Suspension Intraperitoneal Injection Model. Front Med (Lausanne) 9:765805,2022
Tsuchida T, Hayakawa M, Kawahara S, Kumano O: Thrombin generation capacity is enhanced by low antithrombin activity and depends on the activity of the related coagulation factors. Thromb J 20:29,2022
Tsuchida T, Hayakawa M: Author Response Letter: “Correspondence: Is there an association between centre volume and survival or neurological outcomes among out-of-hospital cardiac arrest patients?” BMC Emerg Med 22:198 ,2022
Inoue A, Hifumi T, Sakamoto T, Okamoto H, Kunikata J, Yokoi H, Sawano H, Egawa Y, Kato S, Sugiyama K, Bunya N, Kasai T, Ijuin S, Nakayama S, Kanda J, Kanou S, Takiguchi T, Yokobori S, Takada H, Inoue K, Takeuchi I, Honzawa H, Kobayashi M, Hamagami T, Takayama W, Otomo Y, Maekawa K, Shimizu T, Nara S, Nasu M, Takahashi K, Hagiwara Y, Kushimoto S, Fukuda R, Ogura T, Shiraishi SI, Zushi R, Otani N, Kikuchi M, Watanabe K, Nakagami T, Shoko T, Kitamura N, Otani T, Matsuoka Y, Aoki M, Sakuraya M, Arimoto H, Homma K, Naito H, Nakao S, Okazaki T, Tahara Y, Kuroda Y: Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan. Crit Care 26:129,2022
Katabami K, Kimura T, Hirata T, Tamakoshi A: Risk Factors of Mortality from Foreign Bodies in the Respiratory Tract: The Japan Collaborative Cohort Study. Intern Med 61:1353-1359,2022
Yamamoto R, Kaito D, Homma K, Endo A, Tagami T, Suzuki M, Umetani N, Yagi M, Nashiki E, Suhara T, Nagata H, Kabata H, Fukunaga K, Yamakawa K, Hayakawa M, Ogura T, Hirayama A, Yasunaga H, Sasaki J: Early intubation and decreased in-hospital mortality in patients with coronavirus disease 2019. Crit Care 26:124,2022
Goto T, Kudo D, Uchimido R, Hayakawa M, Yamakawa K, Abe T, Shiraishi A, Kushimoto S: Web-based application for predicting the potential target phenotype for recombinant human thrombomodulin therapy in patients with sepsis: analysis of three multicentre registries. Crit Care 26:145,2022
Wada T, Yamakawa K, Kabata D, Abe T, Ogura H, Shiraishi A, Saitoh D, Kushimoto S, Fujishima S, Mayumi T, Hifumi T, Shiino Y, Nakada TA, Tarui T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S, Gando S: Age-related differences in the survival benefit of the administration of antithrombin, recombinant human thrombomodulin, or their combination in sepsis. Sci Rep 12:9304,2022
Mori H, Kataoka Y, Harada-Shirado K, Kawano N, Hayakawa M, Seki Y, Uchiyama T, Yamakawa K, Ishikura H, Irie Y, Nishio K, Yada N, Okamoto K, Yamada S, Ikezoe T: Prognostic value of serum high mobility group box 1 protein and histone H3 levels in patients with disseminated intravascular coagulation: a multicenter prospective cohort study. Thromb J 20:33,2022
Tominaga N, Hayakawa M, Yokobori S: Blush in Lung Contusions Is Not Rare and Has a High Risk of Mortality in Patients With Blunt Chest Trauma. Front Med (Lausanne) 9:858511,2022
Tsuchida T, Ono K, Maekawa K, Hayamizu M, Hayakawa M: Effect of annual hospital admissions of out-of-hospital cardiac arrest patients on prognosis following cardiac arrest. BMC Emerg Med 22:121,2022
Mizugaki A, Wada T, Tsuchida T, Gando S: Association of Histones With Coagulofibrinolytic Responses and Organ Dysfunction in Adult Post-cardiac Arrest Syndrome. Front Cardiovasc Med 9:885406,2022
Gando S, Shiraishi A, Wada T, Yamakawa K, Fujishima S, Saitoh D, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Shiraishi SI, Shiino Y, Nakada TA, Okamoto K, Sakamoto Y, Hagiwara A, Fujimi S, Umemura Y, Otomo Y: Effects of tranexamic acid on coagulofibrinolytic markers during the early stage of severe trauma: A propensity score-matched analysis. Medicine (Baltimore) 101:e29711,2022
Endo A, Yamakawa K, Tagami T, Umemura Y, Takahashi K, Nagasawa H, Araki Y, Kojima M, Sera T, Yagi M, Yamamoto R, Takahashi J, Nakane M, Takeda C, Narita C, Kazuma S, Okura H, Takahashi H, Wada T, Tahara S, Matsuoka A, Masaki T, Shiraishi A, Shimoyama K, Yokokawa Y, Nakamura R, Sageshima H, Yanagida Y, Otomo Y: Optimal target blood pressure in elderly with septic shock (OPTPRESS) trial: study protocol for a randomized controlled trial. Trials 23: 799,2022
Mori H, Kataoka Y, Harada-Shirado K, Kawano N, Hayakawa M, Seki Y, Uchiyama T, Yamakawa K, Ishikura H, Irie Y, Nishio K, Yada N, Okamoto K,Yamada S, Ikezoe T: Correction: Prognostic value of plasma high mobility group box 1 protein and histone H3 levels in patients with disseminated intravascular coagulation: a multicenter prospective cohort study. Thromb J 20:49,2022
Itagaki Y, Yoshida N, Banno M, Momosaki R, Yamada K, Hayakawa M: Efficacy of albumin with diuretics in mechanically ventilated patients with hypoalbuminemia: A systematic review and meta-analysis. Medicine (Baltimore) 101: e30276,2022
Takahashi M, Wada T, Nakae R, Fujiki Y, Kanaya T, Takayama Y, Suzuki G, Naoe Y, Yokobori S: Antithrombin activity levels for predicting long-term outcomes in the early phase of isolated traumatic brain injury. Front Immunol 13: 981826,2022
Itagaki Y, Hayakawa M, Maekawa K, Kodate A, Moriki K, Takahashi Y, Sageshima H: Early prediction model of brain death in out-of-hospital cardiac arrest patients: a single-center retrospective and internal validation analysis. BMC Emerg Med 22: 177,2022
Takauji S, Hayakawa M, Yamada D, Tian T, Minowa K, Inoue A, Fujimoto Y, Isokawa S, Miura N, Endo T, Irie J, Otomo G, Sato H, Bando K, Suzuki T, Toyohara T, Tomita A, Iwahara M, Murata S, Shimazaki J, Matsuyoshi T, Yoshizawa J, Nitta K, Sato Y: Outcome of extracorporeal membrane oxygenation use in severe accidental hypothermia with cardiac arrest and circulatory instability: a multicentre, prospective, observational study in Japan (ICE-CRASH study). Resuscitation,2022
Wada T, Shiraishi A, Gando S, Kabata D, Yamakawa K, Fujishima S, Saitoh D, Kushimoto S, Ogura H, Abe T, Mayumi T, Otomo Y: Association of antithrombin with development of trauma-induced disseminated intravascular coagulation and outcomes. Front Immunol 13: 1026163,2022
Mizugaki A, Wada T, Tsuchida T, Oda Y, Kayano K, Yamakawa K, Tanaka S: Neutrophil phenotypes implicated in the pathophysiology of post-traumatic sepsis. Front Med (Lausanne) 9: 982399,2022
Amagasa S, Kashiura M, Yasuda H, Hayakawa M, Yamakawa K, Endo A, Ogura T, Hirayama A, Yasunaga H, Tagami T: Relationship between institutional intensive care volume prior to the COVID-19 pandemic and in-hospital death in ventilated patients with severe COVID-19. Sci Rep 12: 22318,2022
症例報告（英文）
Semba A, Sato T, Tsuchida T: The Moment of Left Ventricular Free-wall Rupture. Intern Med 61: 2989-2990,2022
Oyasu T, Hayakawa M, Ebuoka N, Oba: Ductus arteriosus banding to regulate excessive pulmonary blood flow in a neonate with necrotizing enterocolitis and complex congenital heart disease, including pulmonary atresia and total anomalous pulmonary venous return: a case report. J Cardiothorac Surg 17: 327,2022
定本 圭弘，早川 峰司：【DIC・関連疾患・COVID-19と臨床検査】血栓止血関連疾患の症例報告 播種性血管内凝固(DIC) トロンボモデュリンアルファ(遺伝子組換え)製剤を使用した症例 Land-Mark in Thrombosis & Haemostasis:124-125,2022
国際学会
一般演題
Osawa I, Goto T, Kudo D,Abe T, Hayakawa M, Shiraishi A, Uchimido R, Yamakawa K, Doi K, Kushimoto S. A Machine Learning-Based Estimation of Potential Targets of Polymyxin-B Hemoperfusion Use for Sepsis SCCM, 2022 Critical Care Congress, 18-21 April 2022, (Web参加)
Kumano O, Tsuchida T, Mineji Hayakawa M. The characterization of clot-fibrinolysis waveform analysis and the investigation of usefulness in critical care patients with enhanced or suppressed fibrinolysis The International Society on Thrombosis and Haemostasis 2022, SSC on DIC, 9-13, July 2022, London (Web参加)
Kumano O, Tsuchida T, Mineji Hayakawa M. The validation of new global fibrinolysis capacity assays in high tPA concentration situation and the comparison with thromboelastgraphy. The International Society on Thrombosis and Haemostasis 2022, SSC on DIC, 9-13, July 2022, London (Web参加)
Wada T. Thromboplasminflammation in COVID-19 Coagulopathy: Three viewpoints for Diagnosis and Therapeutic Strategies The International Society on Thrombosis and Haemostasis 2022, SSC on DIC, 9-13, July 2022, London (Web参加)
